ROLE OF THE ATPASE/HELICASE MALELESS (MLE) IN THE ASSEMBLY, TARGETING, SPREADING AND FUNCTION OF THE MALE-SPECIFIC LETHAL (MSL) COMPLEX OF DROSOPHILA

Role of the ATPase/helicase maleless (MLE) in the assembly, targeting, spreading and function of the male-specific lethal (MSL) complex of Drosophila

Abstract Background The male-specific lethal (MSL) complex of Drosophila remodels the chromatin of the X chromosome Collections in males to enhance the level of transcription of most X-linked genes, and thereby achieve dosage compensation.The core complex consists of five proteins and one of two non-coding RNAs.One of the proteins, MOF (males absen

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